Difference between revisions of "YMR159C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004769 YMR159C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG16 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ATG16 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:574928..574476 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004769 | ||
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| − | '''Description of | + | '''Description of YMR159C:''' Conserved protein that interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which localize to the pre-autophagosomal structure and are required for autophagy<ref name='S000069879'>Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 {{SGDpaper|S000069879}} PMID 11897782</ref><ref name='S000120213'>Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 {{SGDpaper|S000120213}} PMID 17204848</ref><ref name='S000040381'>Mizushima N, et al. (1999) Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 18(14):3888-96 {{SGDpaper|S000040381}} PMID 10406794</ref><ref name='S000068967'>Suzuki K, et al. (2001) The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20(21):5971-81 |
| − | {{SGDpaper| | + | {{SGDpaper|S000068967}} PMID 11689437</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR159C |
| Gene name | ATG16 |
| Aliases | APG15, APG16, CVT11, SAP18 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:574928..574476 |
| Primary SGDID | S000004769 |
Description of YMR159C: Conserved protein that interacts with Atg12p-Atg5p conjugates to form Atg12p-Atg5p-Atg16p multimers, which localize to the pre-autophagosomal structure and are required for autophagy[1][2][3][4]
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References
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- ↑ Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 SGD PMID 11897782
- ↑ Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 SGD PMID 17204848
- ↑ Mizushima N, et al. (1999) Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway. EMBO J 18(14):3888-96 SGD PMID 10406794
- ↑ Suzuki K, et al. (2001) The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 20(21):5971-81 SGD PMID 11689437
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