Difference between revisions of "YMR106C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004712 YMR106C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YKU80 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YKU80 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:480190..478301 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004712 | ||
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| − | '''Description of | + | '''Description of YMR106C:''' Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair<ref name='S000074970'>Bertuch AA and Lundblad V (2003) The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol 23(22):8202-15 {{SGDpaper|S000074970}} PMID 14585978</ref><ref name='S000055510'>Boulton SJ and Jackson SP (1996) Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res 24(23):4639-48 {{SGDpaper|S000055510}} PMID 8972848</ref><ref name='S000047483'>Boulton SJ and Jackson SP (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17(6):1819-28 {{SGDpaper|S000047483}} PMID 9501103</ref><ref name='S000052504'>Laroche T, et al. (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8(11):653-6 {{SGDpaper|S000052504}} PMID 9635192</ref><ref name='S000039233'>Martin SG, et al. (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97(5):621-33 {{SGDpaper|S000039233}} PMID 10367891</ref><ref name='S000041209'>Milne GT, et al. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4189-98 |
| − | {{SGDpaper| | + | {{SGDpaper|S000041209}} PMID 8754818</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR106C |
| Gene name | YKU80 |
| Aliases | HDF2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:480190..478301 |
| Primary SGDID | S000004712 |
Description of YMR106C: Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair[1][2][3][4][5][6]
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References
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- ↑ Bertuch AA and Lundblad V (2003) The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol 23(22):8202-15 SGD PMID 14585978
- ↑ Boulton SJ and Jackson SP (1996) Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance. Nucleic Acids Res 24(23):4639-48 SGD PMID 8972848
- ↑ Boulton SJ and Jackson SP (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17(6):1819-28 SGD PMID 9501103
- ↑ Laroche T, et al. (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8(11):653-6 SGD PMID 9635192
- ↑ Martin SG, et al. (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97(5):621-33 SGD PMID 10367891
- ↑ Milne GT, et al. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4189-98 SGD PMID 8754818
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