Difference between revisions of "YMR037C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004640 YMR037C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSN2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MSN2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:346517..344403 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004640 |
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| − | '''Description of | + | '''Description of YMR037C:''' Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression<ref name='S000048927'>Gorner W, et al. (1998) Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 12(4):586-97 {{SGDpaper|S000048927}} PMID 9472026</ref><ref name='S000041380'>Martinez-Pastor MT, et al. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J 15(9):2227-35 |
{{SGDpaper|S000041380}} PMID 8641288</ref> | {{SGDpaper|S000041380}} PMID 8641288</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Regulatory ==== | ||
| + | [[Category:Topic:Interactions:Regulatory]] | ||
| + | Regulatory interaction with YBL064c [[Category:Regulatory Interactions with YBL064c]]<br> | ||
| + | YBL064c is up regulated by Msn2p/Msn4p during glucose exhaustion (cells grown in respiratory carbon sources, such as glycerol / ethanol). Exogenously added cAMP represses the induction of YBL064c mRNA expression even in respiratory conditions. <ref name='S000069137'>Monteiro G, et al. (2002) Regulation of mitochondrial thioredoxin peroxidase I expression by two different pathways: one dependent on cAMP and the other on heme. Free Radic Biol Med 32(3):278-88 {{SGDpaper|S000069137}} PMID 11827753</ref> <ref name = 'CAset9246-2003-03-31'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9246 Gisele Monteiro] on 2003-03-31</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR037C |
| Gene name | MSN2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:346517..344403 |
| Primary SGDID | S000004640 |
Description of YMR037C: Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression[1][2]
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Community Commentary
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Interactions
Regulatory
Regulatory interaction with YBL064c
YBL064c is up regulated by Msn2p/Msn4p during glucose exhaustion (cells grown in respiratory carbon sources, such as glycerol / ethanol). Exogenously added cAMP represses the induction of YBL064c mRNA expression even in respiratory conditions. [3] [4]
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References
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- ↑ Gorner W, et al. (1998) Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 12(4):586-97 SGD PMID 9472026
- ↑ Martinez-Pastor MT, et al. (1996) The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE). EMBO J 15(9):2227-35 SGD PMID 8641288
- ↑ Monteiro G, et al. (2002) Regulation of mitochondrial thioredoxin peroxidase I expression by two different pathways: one dependent on cAMP and the other on heme. Free Radic Biol Med 32(3):278-88 SGD PMID 11827753
- ↑ submitted by Gisele Monteiro on 2003-03-31
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