Difference between revisions of "YML106W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004574 YML106W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''URA5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''URA5 '' | ||
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|nowrap| Chr XIII:56773..57453 | |nowrap| Chr XIII:56773..57453 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004574 |
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| − | '''Description of | + | '''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 |
| − | {{SGDpaper| | + | {{SGDpaper|S000048197}} PMID 2182197</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YML106W |
| Gene name | URA5 |
| Aliases | PYR5 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:56773..57453 |
| Primary SGDID | S000004574 |
Description of YML106W: Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10[1][2][3][4]
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References
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- ↑ Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 SGD PMID 371963
- ↑ Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 SGD PMID 5094209
- ↑ de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 SGD PMID 2651891
- ↑ de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 SGD PMID 2182197
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