Difference between revisions of "YML065W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004530 YML065W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ORC1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ORC1 '' | ||
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|nowrap| Chr XIII:142210..144954 | |nowrap| Chr XIII:142210..144954 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004530 |
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| − | '''Description of | + | '''Description of YML065W:''' Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity<ref name='S000069533'>Bell SP (2002) The origin recognition complex: from simple origins to complex functions. Genes Dev 16(6):659-72 {{SGDpaper|S000069533}} PMID 11914271</ref><ref name='S000042829'>Klemm RD, et al. (1997) Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex. Cell 88(4):493-502 |
| − | {{SGDpaper| | + | {{SGDpaper|S000042829}} PMID 9038340</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YML065W |
| Gene name | ORC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:142210..144954 |
| Primary SGDID | S000004530 |
Description of YML065W: Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity[1][2]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Bell SP (2002) The origin recognition complex: from simple origins to complex functions. Genes Dev 16(6):659-72 SGD PMID 11914271
- ↑ Klemm RD, et al. (1997) Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex. Cell 88(4):493-502 SGD PMID 9038340
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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