Difference between revisions of "YLR421C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR421C YLR421C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004413 YLR421C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN13 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN13 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:965557..965087
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|nowrap| Chr XII:965560..965090
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004413
 
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'''Description of {{PAGENAME}}:''' Subunit of the 19S regulatory particle of the 26S proteasome lid<ref name='S000056447'>Verma R, et al. (2000) Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell 11(10):3425-39
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'''Description of YLR421C:''' Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability<ref name='S000126493'>Husnjak K, et al. (2008) Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453(7194):481-488 {{SGDpaper|S000126493}} PMID 18497817</ref><ref name='S000124883'>Seong KM, et al. (2007) Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome. FEBS Lett 581(13):2567-73 {{SGDpaper|S000124883}} PMID 17499717</ref><ref name='S000056447'>Verma R, et al. (2000) Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell 11(10):3425-39
 
  {{SGDpaper|S000056447}} PMID 11029046</ref>
 
  {{SGDpaper|S000056447}} PMID 11029046</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YLR421C
Gene name RPN13
Aliases
Feature type ORF, Verified
Coordinates Chr XII:965560..965090
Primary SGDID S000004413


Description of YLR421C: Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability[1][2][3]




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References

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  1. Husnjak K, et al. (2008) Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453(7194):481-488 SGD PMID 18497817
  2. Seong KM, et al. (2007) Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome. FEBS Lett 581(13):2567-73 SGD PMID 17499717
  3. Verma R, et al. (2000) Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell 11(10):3425-39 SGD PMID 11029046

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