Difference between revisions of "YLR293C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004284 YLR293C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GSP1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GSP1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XII: | + | |nowrap| Chr XII:721430..720771 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004284 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004284 | ||
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− | '''Description of YLR293C:''' Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog<ref name=' | + | '''Description of YLR293C:''' Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog<ref name='S000047010'>Becker J, et al. (1995) RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. J Biol Chem 270(20):11860-5 {{SGDpaper|S000047010}} PMID 7744835</ref><ref name='S000042505'>Belhumeur P, et al. (1993) GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization. Mol Cell Biol 13(4):2152-61 {{SGDpaper|S000042505}} PMID 8455603</ref><ref name='S000057839'>Floer M and Blobel G (1996) The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein. J Biol Chem 271(10):5313-6 {{SGDpaper|S000057839}} PMID 8621381</ref><ref name='S000040738'>Kadowaki T, et al. (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J 12(7):2929-37 {{SGDpaper|S000040738}} PMID 7687541</ref><ref name='S000045553'>Kunzler M and Hurt EC (1998) Cse1p functions as the nuclear export receptor for importin alpha in yeast. FEBS Lett 433(3):185-90 {{SGDpaper|S000045553}} PMID 9744791</ref><ref name='S000051399'>Lee A, et al. (1994) Site-directed mutagenesis of the yeast PRP20/SRM1 gene reveals distinct activity domains in the protein product. Mol Gen Genet 245(1):32-44 {{SGDpaper|S000051399}} PMID 7845357</ref><ref name='S000051618'>Schlenstedt G, et al. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J 14(21):5367-78 {{SGDpaper|S000051618}} PMID 7489726</ref><ref name='S000044712'>Schlenstedt G, et al. (1997) Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. EMBO J 16(20):6237-49 |
− | {{SGDpaper| | + | {{SGDpaper|S000044712}} PMID 9321403</ref> |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YLR293C |
Gene name | GSP1 |
Aliases | CNR1, CST17 |
Feature type | ORF, Verified |
Coordinates | Chr XII:721430..720771 |
Primary SGDID | S000004284 |
Description of YLR293C: Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog[1][2][3][4][5][6][7][8]
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References
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- ↑ Becker J, et al. (1995) RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. J Biol Chem 270(20):11860-5 SGD PMID 7744835
- ↑ Belhumeur P, et al. (1993) GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization. Mol Cell Biol 13(4):2152-61 SGD PMID 8455603
- ↑ Floer M and Blobel G (1996) The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein. J Biol Chem 271(10):5313-6 SGD PMID 8621381
- ↑ Kadowaki T, et al. (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J 12(7):2929-37 SGD PMID 7687541
- ↑ Kunzler M and Hurt EC (1998) Cse1p functions as the nuclear export receptor for importin alpha in yeast. FEBS Lett 433(3):185-90 SGD PMID 9744791
- ↑ Lee A, et al. (1994) Site-directed mutagenesis of the yeast PRP20/SRM1 gene reveals distinct activity domains in the protein product. Mol Gen Genet 245(1):32-44 SGD PMID 7845357
- ↑ Schlenstedt G, et al. (1995) Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J 14(21):5367-78 SGD PMID 7489726
- ↑ Schlenstedt G, et al. (1997) Yrb4p, a yeast ran-GTP-binding protein involved in import of ribosomal protein L25 into the nucleus. EMBO J 16(20):6237-49 SGD PMID 9321403
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