Difference between revisions of "YLR139C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR139C YLR139C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004129 YLR139C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SLS1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SLS1 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
−
|nowrap| Chr XII:423474..421543
+
|nowrap| Chr XII:423473..421542
 
|-
 
|-
−
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004129
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of {{PAGENAME}}:''' Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV; coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery<ref name='S000073179'>Rodeheffer MS and Shadel GS (2003) Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem 278(20):18695-701 {{SGDpaper|S000073179}} PMID 12637560</ref><ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref><ref name='S000041084'>Rouillard JM, et al. (1996) SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion. Mol Gen Genet 252(6):700-8
+
'''Description of YLR139C:''' Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery<ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref><ref name='S000073179'>Rodeheffer MS and Shadel GS (2003) Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem 278(20):18695-701 {{SGDpaper|S000073179}} PMID 12637560</ref><ref name='S000041084'>Rouillard JM, et al. (1996) SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion. Mol Gen Genet 252(6):700-8
 
  {{SGDpaper|S000041084}} PMID 8917313</ref>
 
  {{SGDpaper|S000041084}} PMID 8917313</ref>
 
<br>
 
<br>
Line 23: Line 24:
 
<br>
 
<br>
 
<br>
 
<br>
−
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
=== Interactions ===
 +
[[Category:Topic:Interactions]]
 +
==== Genetic ====
 +
[[Category:Topic:Interactions:Genetic]]
 +
YLR139C is a suppressor of  MTF2 [[Category:Genetic Interaction with MTF2]]
 +
 +
 +
'''Strain Background''': DBY2006<br>
 +
'''Genotype''': ACB1<br>
 +
'''Mutation type(s)''': null
 +
 +
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
  
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 06:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YLR139C
Gene name SLS1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:423473..421542
Primary SGDID S000004129


Description of YLR139C: Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Genetic

YLR139C is a suppressor of MTF2


Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null

The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [1] [4]




<protect>

References

See Help:References on how to add references

  1. ↑ 1.0 1.1 Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 SGD PMID 11805046
  2. ↑ Rodeheffer MS and Shadel GS (2003) Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J Biol Chem 278(20):18695-701 SGD PMID 12637560
  3. ↑ Rouillard JM, et al. (1996) SLS1, a new Saccharomyces cerevisiae gene involved in mitochondrial metabolism, isolated as a syntheticlethal in association with an SSM4 deletion. Mol Gen Genet 252(6):700-8 SGD PMID 8917313
  4. ↑ submitted by Gerald Shadel on 2003-06-05

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YLR139C&oldid=348390"