Difference between revisions of "YLR103C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004093 YLR103C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDC45 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CDC45 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:345941..343989 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004093 |
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| − | '''Description of | + | '''Description of YLR103C:''' DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes<ref name='S000074822'>McKie JM, et al. (1998) Direct selection of conserved cDNAs from the DiGeorge critical region: isolation of a novel CDC45-like gene. Genome Res 8(8):834-41 {{SGDpaper|S000074822}} PMID 9724329</ref><ref name='S000042473'>Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68:649-86 |
{{SGDpaper|S000042473}} PMID 10872463</ref> | {{SGDpaper|S000042473}} PMID 10872463</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR103C |
| Gene name | CDC45 |
| Aliases | SLD4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:345941..343989 |
| Primary SGDID | S000004093 |
Description of YLR103C: DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes[1][2]
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References
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