Difference between revisions of "YLR043C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR043C YLR043C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004033 YLR043C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRX1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr XII:232014..231703
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|nowrap| Chr XII:232013..231702
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004033
 
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'''Description of {{PAGENAME}}:''' Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance<ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000069486'>Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 {{SGDpaper|S000069486}} PMID 11929546</ref><ref name='S000057828'>Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 {{SGDpaper|S000057828}} PMID 8603912</ref><ref name='S000052969'>Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 {{SGDpaper|S000052969}} PMID 9813082</ref><ref name='S000051462'>Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 {{SGDpaper|S000051462}} PMID 9382859</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 {{SGDpaper|S000048402}} PMID 9015301</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73
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'''Description of YLR043C:''' Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance<ref name='S000051462'>Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 {{SGDpaper|S000051462}} PMID 9382859</ref><ref name='S000069486'>Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 {{SGDpaper|S000069486}} PMID 11929546</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 {{SGDpaper|S000047291}} PMID 10037727</ref><ref name='S000052969'>Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 {{SGDpaper|S000052969}} PMID 9813082</ref><ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000057828'>Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 {{SGDpaper|S000057828}} PMID 8603912</ref><ref name='S000048402'>Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR043C
Gene name TRX1
Aliases LMA1
Feature type ORF, Verified
Coordinates Chr XII:232013..231702
Primary SGDID S000004033


Description of YLR043C: Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance[1][2][3][4][5][6][7]




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References

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  1. Jump up ↑ Barlowe C (1997) Coupled ER to Golgi transport reconstituted with purified cytosolic proteins. J Cell Biol 139(5):1097-108 SGD PMID 9382859
  2. Jump up ↑ Garrido EO and Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress induced by hydroperoxides. Mol Microbiol 43(4):993-1003 SGD PMID 11929546
  3. Jump up ↑ Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 SGD PMID 10037727
  4. Jump up ↑ Spang A and Schekman R (1998) Reconstitution of retrograde transport from the Golgi to the ER in vitro. J Cell Biol 143(3):589-99 SGD PMID 9813082
  5. Jump up ↑ Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 SGD PMID 12410842
  6. Jump up ↑ Xu Z and Wickner W (1996) Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae. J Cell Biol 132(5):787-94 SGD PMID 8603912
  7. Jump up ↑ Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301

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