Difference between revisions of "YLR035C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004025 YLR035C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MLH2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:214456..212369 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004025 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004025 | ||
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| − | '''Description of YLR035C:''' Protein | + | '''Description of YLR035C:''' Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p<ref name='S000077475'>Abdullah MF, et al. (2004) A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast. Cytogenet Genome Res 107(3-4):180-90 {{SGDpaper|S000077475}} PMID 15467363</ref><ref name='S000042567'>Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 {{SGDpaper|S000042567}} PMID 10679328</ref><ref name='S000055563'>Wang TF, et al. (1999) Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A 96(24):13914-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000055563}} PMID 10570173</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YLR035C |
| Gene name | MLH2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:214456..212369 |
| Primary SGDID | S000004025 |
Description of YLR035C: Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Abdullah MF, et al. (2004) A role for the MutL homologue MLH2 in controlling heteroduplex formation and in regulating between two different crossover pathways in budding yeast. Cytogenet Genome Res 107(3-4):180-90 SGD PMID 15467363
- ↑ Harfe BD, et al. (2000) Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. Curr Biol 10(3):145-8 SGD PMID 10679328
- ↑ Wang TF, et al. (1999) Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A 96(24):13914-9 SGD PMID 10570173
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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