Difference between revisions of "YLL049W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003972 YLL049W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003972 YLL049W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''LDB18 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''LDB18 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:40665..41204
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|nowrap| Chr XII:40666..41205
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003972
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003972
 
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'''Description of YLL049W:''' Protein of unknown function; required for nuclear migration; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface<ref name='S000082235'>Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 {{SGDpaper|S000082235}} PMID 15993632</ref><ref name='S000116012'>Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1():2005.0026
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'''Description of YLL049W:''' Component of the dynactin complex, which is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24<ref name='S000125431'>Amaro IA, et al. (2008) The Saccharomyces cerevisiae Homolog of p24 Is Essential for Maintaining the Association of p150Glued With the Dynactin Complex. Genetics 178(2):703-9 {{SGDpaper|S000125431}} PMID 18245366</ref><ref name='S000082235'>Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 {{SGDpaper|S000082235}} PMID 15993632</ref><ref name='S000116012'>Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1():2005.0026
 
  {{SGDpaper|S000116012}} PMID 16729061</ref>
 
  {{SGDpaper|S000116012}} PMID 16729061</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLL049W
Gene name LDB18
Aliases
Feature type ORF, Verified
Coordinates Chr XII:40666..41205
Primary SGDID S000003972


Description of YLL049W: Component of the dynactin complex, which is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24[1][2][3]




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References

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  1. Amaro IA, et al. (2008) The Saccharomyces cerevisiae Homolog of p24 Is Essential for Maintaining the Association of p150Glued With the Dynactin Complex. Genetics 178(2):703-9 SGD PMID 18245366
  2. Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 SGD PMID 15993632
  3. Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1():2005.0026 SGD PMID 16729061

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