Difference between revisions of "YLL006W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLL006W YLL006W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003929 YLL006W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MMM1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MMM1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:136585..137865
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|nowrap| Chr XII:136586..137866
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003929
 
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'''Description of {{PAGENAME}}:''' Mitochondrial outer membrane protein required for normal mitochondrial morphology and mtDNA stability; involved in tethering mitochondria to the actin cytoskeleton and in anchoring mtDNA nucleoids<ref name='S000059964'>Hobbs AE, et al. (2001) Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol 152(2):401-10 {{SGDpaper|S000059964}} PMID 11266455</ref><ref name='S000051815'>Burgess SM, et al. (1994) MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol 126(6):1375-91 {{SGDpaper|S000051815}} PMID 8089172</ref><ref name='S000040782'>Boldogh I, et al. (1998) Interaction between mitochondria and the actin cytoskeleton in budding yeast requires two integral mitochondrial outer membrane proteins, Mmm1p and Mdm10p. J Cell Biol 141(6):1371-81
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'''Description of YLL006W:''' ER integral membrane protein, component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth<ref name='S000040782'>Boldogh I, et al. (1998) Interaction between mitochondria and the actin cytoskeleton in budding yeast requires two integral mitochondrial outer membrane proteins, Mmm1p and Mdm10p. J Cell Biol 141(6):1371-81 {{SGDpaper|S000040782}} PMID 9628893</ref><ref name='S000051815'>Burgess SM, et al. (1994) MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol 126(6):1375-91 {{SGDpaper|S000051815}} PMID 8089172</ref><ref name='S000059964'>Hobbs AE, et al. (2001) Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol 152(2):401-10 {{SGDpaper|S000059964}} PMID 11266455</ref><ref name='S000132272'>Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 {{SGDpaper|S000132272}} PMID 19556461</ref><ref name='S000123755'>Meisinger C, et al. (2007) The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J 26(9):2229-39
  {{SGDpaper|S000040782}} PMID 9628893</ref>
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  {{SGDpaper|S000123755}} PMID 17410204</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YLL006W
Gene name MMM1
Aliases YME6
Feature type ORF, Verified
Coordinates Chr XII:136586..137866
Primary SGDID S000003929


Description of YLL006W: ER integral membrane protein, component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth[1][2][3][4][5]




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References

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  1. Boldogh I, et al. (1998) Interaction between mitochondria and the actin cytoskeleton in budding yeast requires two integral mitochondrial outer membrane proteins, Mmm1p and Mdm10p. J Cell Biol 141(6):1371-81 SGD PMID 9628893
  2. Burgess SM, et al. (1994) MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol 126(6):1375-91 SGD PMID 8089172
  3. Hobbs AE, et al. (2001) Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol 152(2):401-10 SGD PMID 11266455
  4. Kornmann B, et al. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325(5939):477-81 SGD PMID 19556461
  5. Meisinger C, et al. (2007) The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J 26(9):2229-39 SGD PMID 17410204

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