Difference between revisions of "YJR117W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJR117W YJR117W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003878 YJR117W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STE24 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STE24 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:642001..643362
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|nowrap| Chr X:642007..643368
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003878
 
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'''Description of {{PAGENAME}}:''' Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans<ref name='S000068762'>Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806 {{SGDpaper|S000068762}} PMID 11581258</ref><ref name='S000048019'>Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 {{SGDpaper|S000048019}} PMID 9015299</ref><ref name='S000039448'>Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49
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'''Description of YJR117W:''' Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans<ref name='S000048235'>Boyartchuk VL, et al. (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275(5307):1796-800 {{SGDpaper|S000048235}} PMID 9065405</ref><ref name='S000048019'>Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 {{SGDpaper|S000048019}} PMID 9015299</ref><ref name='S000039448'>Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49 {{SGDpaper|S000039448}} PMID 9700155</ref><ref name='S000068762'>Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806
  {{SGDpaper|S000039448}} PMID 9700155</ref>
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  {{SGDpaper|S000068762}} PMID 11581258</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YJR117W
Gene name STE24
Aliases AFC1, PIO2
Feature type ORF, Verified
Coordinates Chr X:642007..643368
Primary SGDID S000003878


Description of YJR117W: Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans[1][2][3][4]




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References

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  1. Boyartchuk VL, et al. (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275(5307):1796-800 SGD PMID 9065405
  2. Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 SGD PMID 9015299
  3. Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49 SGD PMID 9700155
  4. Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806 SGD PMID 11581258

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