Difference between revisions of "YJR117W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003878 YJR117W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE24 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE24 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:642007..643368 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003878 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003878 | ||
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| − | '''Description of YJR117W:''' Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans<ref name='S000048019'>Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 {{SGDpaper|S000048019}} PMID 9015299</ref><ref name='S000039448'>Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49 {{SGDpaper|S000039448}} PMID 9700155</ref><ref name='S000068762'>Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806 | + | '''Description of YJR117W:''' Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans<ref name='S000048235'>Boyartchuk VL, et al. (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275(5307):1796-800 {{SGDpaper|S000048235}} PMID 9065405</ref><ref name='S000048019'>Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 {{SGDpaper|S000048019}} PMID 9015299</ref><ref name='S000039448'>Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49 {{SGDpaper|S000039448}} PMID 9700155</ref><ref name='S000068762'>Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806 |
{{SGDpaper|S000068762}} PMID 11581258</ref> | {{SGDpaper|S000068762}} PMID 11581258</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YJR117W |
| Gene name | STE24 |
| Aliases | AFC1, PIO2 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:642007..643368 |
| Primary SGDID | S000003878 |
Description of YJR117W: Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans[1][2][3][4]
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References
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- ↑ Boyartchuk VL, et al. (1997) Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. Science 275(5307):1796-800 SGD PMID 9065405
- ↑ Fujimura-Kamada K, et al. (1997) A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor. J Cell Biol 136(2):271-85 SGD PMID 9015299
- ↑ Tam A, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol 142(3):635-49 SGD PMID 9700155
- ↑ Tam A, et al. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. J Biol Chem 276(50):46798-806 SGD PMID 11581258
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