Difference between revisions of "YJR086W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003846 YJR086W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE18 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STE18 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr X: | + | |nowrap| Chr X:586068..586400 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003846 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003846 | ||
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− | '''Description of YJR086W:''' G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling<ref name='S000045208'>Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 {{SGDpaper|S000045208}} PMID 2536595 | + | '''Description of YJR086W:''' G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling<ref name='S000046851'>Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 {{SGDpaper|S000046851}} PMID 10523659</ref><ref name='S000045208'>Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 |
− | + | {{SGDpaper|S000045208}} PMID 2536595</ref> | |
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Latest revision as of 07:45, 23 January 2012
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Systematic name | YJR086W |
Gene name | STE18 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:586068..586400 |
Primary SGDID | S000003846 |
Description of YJR086W: G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling[1][2]
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References
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- ↑ Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 SGD PMID 10523659
- ↑ Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 SGD PMID 2536595
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