Difference between revisions of "YJL208C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003744 YJL208C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUC1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUC1 '' | ||
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|nowrap| Chr X:41183..40194 | |nowrap| Chr X:41183..40194 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003744 |
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| − | '''Description of | + | '''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 {{SGDpaper|S000045493}} PMID 2836792</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000052577}} PMID 8087883</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YJL208C |
| Gene name | NUC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:41183..40194 |
| Primary SGDID | S000003744 |
Description of YJL208C: Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 SGD PMID 17471024
- ↑ Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 SGD PMID 17244531
- ↑ Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 SGD PMID 3286639
- ↑ Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 SGD PMID 2836792
- ↑ Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 SGD PMID 8087883
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