Difference between revisions of "YJL164C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(10 intermediate revisions by 2 users not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL164C YJL164C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003700 YJL164C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TPK1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TPK1 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
−
|nowrap| Chr X:111153..109960
+
|nowrap| Chr X:111159..109966
 
|-
 
|-
−
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003700
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of {{PAGENAME}}:''' Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; inhibits filamentous growth<ref name='S000051906'>Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87 {{SGDpaper|S000051906}} PMID 10373537</ref><ref name='S000043708'>Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 {{SGDpaper|S000043708}} PMID 3037314</ref><ref name='S000042460'>Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 {{SGDpaper|S000042460}} PMID 8641464</ref><ref name='S000042132'>Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87
+
'''Description of YJL164C:''' cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p<ref name='S000042460'>Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 {{SGDpaper|S000042460}} PMID 8641464</ref><ref name='S000043708'>Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 {{SGDpaper|S000043708}} PMID 3037314</ref><ref name='S000042132'>Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87
 
  {{SGDpaper|S000042132}} PMID 3036373</ref>
 
  {{SGDpaper|S000042132}} PMID 3036373</ref>
 
<br>
 
<br>
Line 23: Line 24:
 
<br>
 
<br>
 
<br>
 
<br>
−
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
=== Interactions ===
 +
[[Category:Topic:Interactions]]
 +
==== Genetic ====
 +
[[Category:Topic:Interactions:Genetic]]
 +
 +
'''Strain Background''': S288C, W303 (''see [[CommunityW303.html|detailed notes]] from Rodney Rothstein and Stephan Bartsch for the W303 strain used in the study''), industrial<br>
 +
Genetic interaction with ATF1 [[Category:Genetic Interactions with ATF1]]<br>'''Mutation type(s)''': deletion/partial inactivating
 +
 +
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. <ref name='S000075255'>Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 {{SGDpaper|S000075255}} PMID 14654433</ref> <ref name = 'CAset9888-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9888 Kevin J Verstrepen] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
  
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 06:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YJL164C
Gene name TPK1
Aliases PKA1, SRA3
Feature type ORF, Verified
Coordinates Chr X:111159..109966
Primary SGDID S000003700


Description of YJL164C: cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Genetic

Strain Background: S288C, W303 (see detailed notes from Rodney Rothstein and Stephan Bartsch for the W303 strain used in the study), industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating

ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [4] [5]




<protect>

References

See Help:References on how to add references

  1. ↑ Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
  2. ↑ Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
  3. ↑ Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
  4. ↑ Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
  5. ↑ submitted by Kevin J Verstrepen on 2004-03-04

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YJL164C&oldid=347951"