Difference between revisions of "YJL127C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003663 YJL127C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003663 YJL127C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPT10 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPT10 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:184217..182295
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|nowrap| Chr X:184220..182298
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003663
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003663
 
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'''Description of YJL127C:''' Putative histone acetylase, sequence-specific activator of histone genes, binds specifically and highly cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box<ref name='S000086891'>Eriksson PR, et al. (2005) Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements. Mol Cell Biol 25(20):9127-37 {{SGDpaper|S000086891}} PMID 16199888</ref><ref name='S000071387'>Shen CH, et al. (2002) Targeted histone acetylation at the yeast CUP1 promoter requires the transcriptional activator, the TATA boxes, and the putative histone acetylase encoded by SPT10. Mol Cell Biol 22(18):6406-16 {{SGDpaper|S000071387}} PMID 12192040</ref><ref name='S000049994'>Yamashita I (1993) Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):616-26
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'''Description of YJL127C:''' Putative histone acetylase with a role in transcriptional silencing, sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box<ref name='S000140064'>Chang JS and Winston F (2011) Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae. Eukaryot Cell 10(1):118-29 {{SGDpaper|S000140064}} PMID 21057056</ref><ref name='S000086891'>Eriksson PR, et al. (2005) Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements. Mol Cell Biol 25(20):9127-37 {{SGDpaper|S000086891}} PMID 16199888</ref><ref name='S000071387'>Shen CH, et al. (2002) Targeted histone acetylation at the yeast CUP1 promoter requires the transcriptional activator, the TATA boxes, and the putative histone acetylase encoded by SPT10. Mol Cell Biol 22(18):6406-16 {{SGDpaper|S000071387}} PMID 12192040</ref><ref name='S000049994'>Yamashita I (1993) Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):616-26
 
  {{SGDpaper|S000049994}} PMID 8264536</ref>
 
  {{SGDpaper|S000049994}} PMID 8264536</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YJL127C
Gene name SPT10
Aliases CRE1, SUD1
Feature type ORF, Verified
Coordinates Chr X:184220..182298
Primary SGDID S000003663


Description of YJL127C: Putative histone acetylase with a role in transcriptional silencing, sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box[1][2][3][4]




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References

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  1. Chang JS and Winston F (2011) Spt10 and Spt21 Are Required for Transcriptional Silencing in Saccharomyces cerevisiae. Eukaryot Cell 10(1):118-29 SGD PMID 21057056
  2. Eriksson PR, et al. (2005) Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements. Mol Cell Biol 25(20):9127-37 SGD PMID 16199888
  3. Shen CH, et al. (2002) Targeted histone acetylation at the yeast CUP1 promoter requires the transcriptional activator, the TATA boxes, and the putative histone acetylase encoded by SPT10. Mol Cell Biol 22(18):6406-16 SGD PMID 12192040
  4. Yamashita I (1993) Isolation and characterization of the SUD1 gene, which encodes a global repressor of core promoter activity in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):616-26 SGD PMID 8264536

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