Difference between revisions of "YJL058C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL058C YJL058C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003594 YJL058C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIT61 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIT61 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
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|nowrap| Chr X:327868..326237
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|nowrap| Chr X:327873..326242
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003594
 
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'''Description of {{PAGENAME}}:''' Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity<ref name='S000080639'>Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 {{SGDpaper|S000080639}} PMID 15689497</ref><ref name='S000081257'>Ho HL, et al. (2005) Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex. Curr Genet 47(5):273-88 {{SGDpaper|S000081257}} PMID 15809876</ref><ref name='S000075967'>Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 {{SGDpaper|S000075967}} PMID 14736892</ref><ref name='S000073348'>SGD (2003) Information without a citation in SGD () {{SGDpaper|S000073348}} PMID </ref><ref name='S000072891'>Wedaman KP, et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(3):1204-20 {{SGDpaper|S000072891}} PMID 12631735</ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68
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'''Description of YJL058C:''' Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity<ref name='S000080639'>Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 {{SGDpaper|S000080639}} PMID 15689497</ref><ref name='S000081257'>Ho HL, et al. (2005) Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex. Curr Genet 47(5):273-88 {{SGDpaper|S000081257}} PMID 15809876</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000075967'>Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 {{SGDpaper|S000075967}} PMID 14736892</ref><ref name='S000073348'>SGD (2007) Information without a citation in SGD   {{SGDpaper|S000073348}} PMID </ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000072891'>Wedaman KP, et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(3):1204-20
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YJL058C
Gene name BIT61
Aliases
Feature type ORF, Verified
Coordinates Chr X:327873..326242
Primary SGDID S000003594


Description of YJL058C: Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity[1][2][3][4][5][6][7]




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Community Commentary

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References

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  1. ↑ Fadri M, et al. (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900 SGD PMID 15689497
  2. ↑ Ho HL, et al. (2005) Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex. Curr Genet 47(5):273-88 SGD PMID 15809876
  3. ↑ Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 SGD PMID 12408816
  4. ↑ Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 SGD PMID 14736892
  5. ↑ SGD (2007) Information without a citation in SGD SGD PMID
  6. ↑ Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 SGD PMID 12171921
  7. ↑ Wedaman KP, et al. (2003) Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae. Mol Biol Cell 14(3):1204-20 SGD PMID 12631735

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