Difference between revisions of "YGR240C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR240C YGR240C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003472 YGR240C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PFK1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PFK1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr VII:973739..970776
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|nowrap| Chr VII:973734..970771
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003472
 
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'''Description of {{PAGENAME}}:''' Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes<ref name='S000076070'>Foy JJ and Bhattacharjee JK (1978) Biosynthesis and regulation of fructose-1,6-bisphosphatase and phosphofructokinase in Saccharomyces cerevisiae grown in the presence of glucose and gluconeogenic carbon sources. J Bacteriol 136(2):647-56 {{SGDpaper|S000076070}} PMID 213420</ref><ref name='S000072711'>Newcomb LL, et al. (2003) Glucose regulation of Saccharomyces cerevisiae cell cycle genes. Eukaryot Cell 2(1):143-9 {{SGDpaper|S000072711}} PMID 12582131</ref><ref name='S000064406'>Nissler K, et al. (1985) An electron microscopy study of the quarternary structure of yeast phosphofructokinase. Biomed Biochim Acta 44(2):251-9 {{SGDpaper|S000064406}} PMID 2408613</ref><ref name='S000064403'>Otto A, et al. (1986) Kinetic effects of fructose-1,6-bisphosphate on yeast phosphofructokinase. Biomed Biochim Acta 45(7):865-75 {{SGDpaper|S000064403}} PMID 2947575</ref><ref name='S000064401'>Kriegel T, et al. (1987) Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase. Biomed Biochim Acta 46(5):349-55 {{SGDpaper|S000064401}} PMID 2959282</ref><ref name='S000056022'>Lobo Z and Maitra PK (1983) Phosphofructokinase mutants of yeast. Biochemistry and genetics. J Biol Chem 258(3):1444-9 {{SGDpaper|S000056022}} PMID 6218165</ref><ref name='S000049052'>Arvanitidis A and Heinisch JJ (1994) Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis. J Biol Chem 269(12):8911-8
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'''Description of YGR240C:''' Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes<ref name='S000049052'>Arvanitidis A and Heinisch JJ (1994) Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis. J Biol Chem 269(12):8911-8 {{SGDpaper|S000049052}} PMID 8132627</ref><ref name='S000076070'>Foy JJ and Bhattacharjee JK (1978) Biosynthesis and regulation of fructose-1,6-bisphosphatase and phosphofructokinase in Saccharomyces cerevisiae grown in the presence of glucose and gluconeogenic carbon sources. J Bacteriol 136(2):647-56 {{SGDpaper|S000076070}} PMID 213420</ref><ref name='S000064401'>Kriegel T, et al. (1987) Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase. Biomed Biochim Acta 46(5):349-55 {{SGDpaper|S000064401}} PMID 2959282</ref><ref name='S000056022'>Lobo Z and Maitra PK (1983) Phosphofructokinase mutants of yeast. Biochemistry and genetics. J Biol Chem 258(3):1444-9 {{SGDpaper|S000056022}} PMID 6218165</ref><ref name='S000072711'>Newcomb LL, et al. (2003) Glucose regulation of Saccharomyces cerevisiae cell cycle genes. Eukaryot Cell 2(1):143-9 {{SGDpaper|S000072711}} PMID 12582131</ref><ref name='S000064406'>Nissler K, et al. (1985) An electron microscopy study of the quarternary structure of yeast phosphofructokinase. Biomed Biochim Acta 44(2):251-9 {{SGDpaper|S000064406}} PMID 2408613</ref><ref name='S000064403'>Otto A, et al. (1986) Kinetic effects of fructose-1,6-bisphosphate on yeast phosphofructokinase. Biomed Biochim Acta 45(7):865-75
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{{SGDpaper|S000064403}} PMID 2947575</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YGR240C
Gene name PFK1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:973734..970771
Primary SGDID S000003472


Description of YGR240C: Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes[1][2][3][4][5][6][7]




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References

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  1. ↑ Arvanitidis A and Heinisch JJ (1994) Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis. J Biol Chem 269(12):8911-8 SGD PMID 8132627
  2. ↑ Foy JJ and Bhattacharjee JK (1978) Biosynthesis and regulation of fructose-1,6-bisphosphatase and phosphofructokinase in Saccharomyces cerevisiae grown in the presence of glucose and gluconeogenic carbon sources. J Bacteriol 136(2):647-56 SGD PMID 213420
  3. ↑ Kriegel T, et al. (1987) Hydrodynamic studies on the quaternary structure of reacting yeast phosphofructokinase. Biomed Biochim Acta 46(5):349-55 SGD PMID 2959282
  4. ↑ Lobo Z and Maitra PK (1983) Phosphofructokinase mutants of yeast. Biochemistry and genetics. J Biol Chem 258(3):1444-9 SGD PMID 6218165
  5. ↑ Newcomb LL, et al. (2003) Glucose regulation of Saccharomyces cerevisiae cell cycle genes. Eukaryot Cell 2(1):143-9 SGD PMID 12582131
  6. ↑ Nissler K, et al. (1985) An electron microscopy study of the quarternary structure of yeast phosphofructokinase. Biomed Biochim Acta 44(2):251-9 SGD PMID 2408613
  7. ↑ Otto A, et al. (1986) Kinetic effects of fructose-1,6-bisphosphate on yeast phosphofructokinase. Biomed Biochim Acta 45(7):865-75 SGD PMID 2947575

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