Difference between revisions of "YGR206W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003438 YGR206W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MVB12 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MVB12 '' | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YGR206W |
| Gene name | MVB12 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:910432..910737 |
| Primary SGDID | S000003438 |
Description of YGR206W: ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 SGD PMID 17145965
- ↑ Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 SGD PMID 17135292
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 SGD PMID 15883373
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