Difference between revisions of "YGR198W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003430 YGR198W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003430 YGR198W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YPP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YPP1 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YGR198W
Gene name YPP1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:894693..897146
Primary SGDID S000003430


Description of YGR198W: Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene[1][2][3][4]




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Community Commentary

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GFP-tag is more effective at the n-terminal end. Adding an epitope tag at the C-terminus makes the strain somewhat sick and lowers PI4P levels, however, it seems to localize correctly.



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References

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  1. Flower TR, et al. (2007) YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. J Cell Biol 177(6):1091-104 SGD PMID 17576801
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Rodriguez-Pena JM, et al. (1998) The deletion of six ORFs of unknown function from Saccharomyces cerevisiae chromosome VII reveals two essential genes: YGR195w and YGR198w. Yeast 14(9):853-60 SGD PMID 9818723
  4. Zhai C, et al. (2008) Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane. Biochem J 415(3):455-66 SGD PMID 18601652

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References

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See Help:Categories on how to add the wiki page for this gene to a Category </protect>