Difference between revisions of "YGR178C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR178C YGR178C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003410 YGR178C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PBP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PBP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr VII:853220..851052
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|nowrap| Chr VII:853215..851047
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003410
 
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'''Description of {{PAGENAME}}:''' Protein interacting with poly(A)-binding protein Pab1p; likely involved in controlling the extent of mRNA polyadenylation; forms a complex with Mkt1p that may regulate HO translation; interacts with Lsm12p in a copurification assay<ref name='S000115662'>Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 {{SGDpaper|S000115662}} PMID 16702403</ref><ref name='S000076382'>Tadauchi T, et al. (2004) Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex. Mol Cell Biol 24(9):3670-81 {{SGDpaper|S000076382}} PMID 15082763</ref><ref name='S000076045'>Mangus DA, et al. (2004) Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol 24(10):4196-206 {{SGDpaper|S000076045}} PMID 15121841</ref><ref name='S000047789'>Mangus DA, et al. (1998) Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol 18(12):7383-96
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'''Description of YGR178C:''' Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation<ref name='S000128263'>Buchan JR, et al. (2008) P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol 183(3):441-55 {{SGDpaper|S000128263}} PMID 18981231</ref><ref name='S000047789'>Mangus DA, et al. (1998) Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol 18(12):7383-96 {{SGDpaper|S000047789}} PMID 9819425</ref><ref name='S000076045'>Mangus DA, et al. (2004) Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol 24(10):4196-206 {{SGDpaper|S000076045}} PMID 15121841</ref><ref name='S000080674'>Ralser M, et al. (2005) An integrative approach to gain insights into the cellular function of human ataxin-2. J Mol Biol 346(1):203-14 {{SGDpaper|S000080674}} PMID 15663938</ref><ref name='S000076382'>Tadauchi T, et al. (2004) Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex. Mol Cell Biol 24(9):3670-81
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  {{SGDpaper|S000047789}} PMID 9819425</ref>
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  {{SGDpaper|S000076382}} PMID 15082763</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGR178C
Gene name PBP1
Aliases MRS16
Feature type ORF, Verified
Coordinates Chr VII:853215..851047
Primary SGDID S000003410


Description of YGR178C: Component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; similar to human ataxin-2; interacts with Pab1p to regulate mRNA polyadenylation; interacts with Mkt1p to regulate HO translation[1][2][3][4][5]




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References

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  1. ↑ Buchan JR, et al. (2008) P bodies promote stress granule assembly in Saccharomyces cerevisiae. J Cell Biol 183(3):441-55 SGD PMID 18981231
  2. ↑ Mangus DA, et al. (1998) Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol 18(12):7383-96 SGD PMID 9819425
  3. ↑ Mangus DA, et al. (2004) Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol 24(10):4196-206 SGD PMID 15121841
  4. ↑ Ralser M, et al. (2005) An integrative approach to gain insights into the cellular function of human ataxin-2. J Mol Biol 346(1):203-14 SGD PMID 15663938
  5. ↑ Tadauchi T, et al. (2004) Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex. Mol Cell Biol 24(9):3670-81 SGD PMID 15082763

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