Difference between revisions of "YGL252C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003221 YGL252C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RTG2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RTG2 '' | ||
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|nowrap| Chr VII:27484..25718 | |nowrap| Chr VII:27484..25718 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003221 |
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| − | '''Description of | + | '''Description of YGL252C:''' Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p<ref name='S000050990'>Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 {{SGDpaper|S000050990}} PMID 11076970</ref><ref name='S000044921'>Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 {{SGDpaper|S000044921}} PMID 8422683</ref><ref name='S000074762'>Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11 {{SGDpaper|S000074762}} PMID 14536080</ref><ref name='S000043674'>Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15 {{SGDpaper|S000043674}} PMID 10848632</ref><ref name='S000074403'>Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074403}} PMID 11907262</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL252C |
| Gene name | RTG2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:27484..25718 |
| Primary SGDID | S000003221 |
Description of YGL252C: Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p[1][2][3][4][5]
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References
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- ↑ Komeili A, et al. (2000) Mechanism of metabolic control. Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors. J Cell Biol 151(4):863-78 SGD PMID 11076970
- ↑ Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 SGD PMID 8422683
- ↑ Liu Z, et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12(2):401-11 SGD PMID 14536080
- ↑ Sekito T, et al. (2000) Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell 11(6):2103-15 SGD PMID 10848632
- ↑ Sekito T, et al. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell 13(3):795-804 SGD PMID 11907262
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