Difference between revisions of "YGL248W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003217 YGL248W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003217 YGL248W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PDE1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PDE1 ''
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'''Description of YGL248W:''' Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation<ref name='S000055313'>Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50 {{SGDpaper|S000055313}} PMID 9459299</ref><ref name='S000055305'>Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 {{SGDpaper|S000055305}} PMID 9880329</ref><ref name='S000044225'>Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 {{SGDpaper|S000044225}} PMID 6300049</ref><ref name='S000042124'>Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 {{SGDpaper|S000042124}} PMID 10476026</ref><ref name='S000040124'>Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36
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'''Description of YGL248W:''' Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation<ref name='S000055305'>Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 {{SGDpaper|S000055305}} PMID 9880329</ref><ref name='S000040124'>Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 {{SGDpaper|S000040124}} PMID 2824992</ref><ref name='S000042124'>Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 {{SGDpaper|S000042124}} PMID 10476026</ref><ref name='S000044225'>Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 {{SGDpaper|S000044225}} PMID 6300049</ref><ref name='S000055313'>Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50
  {{SGDpaper|S000040124}} PMID 2824992</ref>
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  {{SGDpaper|S000055313}} PMID 9459299</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGL248W
Gene name PDE1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:35653..36762
Primary SGDID S000003217


Description of YGL248W: Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation[1][2][3][4][5]




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References

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  1. Ma P, et al. (1999) The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling. Mol Biol Cell 10(1):91-104 SGD PMID 9880329
  2. Nikawa J, et al. (1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Mol Cell Biol 7(10):3629-36 SGD PMID 2824992
  3. Thevelein JM and de Winde JH (1999) Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33(5):904-18 SGD PMID 10476026
  4. Uno I, et al. (1983) Characterization of a cyclic nucleotide phosphodiesterase-deficient mutant in yeast. J Biol Chem 258(6):3539-42 SGD PMID 6300049
  5. Wera S, et al. (1997) Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae. FEBS Lett 420(2-3):147-50 SGD PMID 9459299

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