Difference between revisions of "YGL247W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003216 YGL247W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003216 YGL247W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BRR6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BRR6 ''
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'''Description of YGL247W:''' Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores<ref name='S000065919'>de Bruyn Kops A and Guthrie C (2001) An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport. EMBO J 20(15):4183-93
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'''Description of YGL247W:''' Essential nuclear envelope integral membrane protein required for nuclear envelope morphology, nuclear pore complex localization, nuclear export; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism<ref name='S000132523'>Hodg CA, et al. (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-151 {{SGDpaper|S000132523}} PMID 20016074</ref><ref name='S000065919'>de Bruyn Kops A and Guthrie C (2001) An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport. EMBO J 20(15):4183-93
 
  {{SGDpaper|S000065919}} PMID 11483521</ref>
 
  {{SGDpaper|S000065919}} PMID 11483521</ref>
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YGL247W
Gene name BRR6
Aliases
Feature type ORF, Verified
Coordinates Chr VII:36933..37526
Primary SGDID S000003216


Description of YGL247W: Essential nuclear envelope integral membrane protein required for nuclear envelope morphology, nuclear pore complex localization, nuclear export; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism[1][2]




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References

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  1. Hodg CA, et al. (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-151 SGD PMID 20016074
  2. de Bruyn Kops A and Guthrie C (2001) An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport. EMBO J 20(15):4183-93 SGD PMID 11483521

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