Difference between revisions of "YGL231C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003200 YGL231C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003200 YGL231C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''EMC4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''EMC4 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YGL231C
Gene name EMC4
Aliases
Feature type ORF, Verified
Coordinates Chr VII:63620..63048
Primary SGDID S000003200


Description of YGL231C: Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; human ortholog TMEM85 may function in apoptosis[1][2]




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References

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  1. Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 SGD PMID 19325107
  2. Ring G, et al. (2008) Transmembrane protein 85 from both human (TMEM85) and yeast (YGL231c) inhibit hydrogen peroxide mediated cell death in yeast. FEBS Lett 582(17):2637-42 SGD PMID 18586032

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