Difference between revisions of "YGL195W"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003163 YGL195W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GCN1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''GCN1 '' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' '' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''AAS103, NDR1'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VII: | + | |nowrap| Chr VII:131525..139543 |
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− | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003163 |
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− | '''Description of | + | '''Description of YGL195W:''' Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA<ref name='S000063198'>Garcia-Barrio M, et al. (2000) Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. EMBO J 19(8):1887-99 {{SGDpaper|S000063198}} PMID 10775272</ref><ref name='S000060332'>Kubota H, et al. (2001) Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. J Biol Chem 276(20):17591-6 |
{{SGDpaper|S000060332}} PMID 11350982</ref> | {{SGDpaper|S000060332}} PMID 11350982</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
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+ | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
+ | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
+ | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YGL195W |
Gene name | GCN1 |
Aliases | AAS103, NDR1 |
Feature type | ORF, Verified |
Coordinates | Chr VII:131525..139543 |
Primary SGDID | S000003163 |
Description of YGL195W: Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA[1][2]
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Contents
Community Commentary
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References
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- ↑ Garcia-Barrio M, et al. (2000) Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. EMBO J 19(8):1887-99 SGD PMID 10775272
- ↑ Kubota H, et al. (2001) Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2. J Biol Chem 276(20):17591-6 SGD PMID 11350982
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