Difference between revisions of "YGL025C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002993 YGL025C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PGD1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PGD1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VII: | + | |nowrap| Chr VII:449957..448764 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002993 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002993 | ||
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− | '''Description of YGL025C:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor<ref name='S000077554'>Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 {{SGDpaper|S000077554}} PMID 15477388</ref><ref name=' | + | '''Description of YGL025C:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor<ref name='S000077554'>Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 {{SGDpaper|S000077554}} PMID 15477388</ref><ref name='S000061610'>Lee M, et al. (2000) Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast. Genetics 155(4):1535-42 {{SGDpaper|S000061610}} PMID 10924455</ref><ref name='S000074926'>Myers LC, et al. (1999) Mediator protein mutations that selectively abolish activated transcription. Proc Natl Acad Sci U S A 96(1):67-72 {{SGDpaper|S000074926}} PMID 9874773</ref><ref name='S000061609'>Papamichos-Chronakis M, et al. (2000) Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. J Biol Chem 275(12):8397-403 {{SGDpaper|S000061609}} PMID 10722672</ref><ref name='S000072496'>Reeves WM and Hahn S (2003) Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation. Mol Cell Biol 23(1):349-58 |
− | {{SGDpaper| | + | {{SGDpaper|S000072496}} PMID 12482986</ref> |
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YGL025C |
Gene name | PGD1 |
Aliases | HRS1, MED3 |
Feature type | ORF, Verified |
Coordinates | Chr VII:449957..448764 |
Primary SGDID | S000002993 |
Description of YGL025C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor[1][2][3][4][5]
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Contents
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References
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- ↑ Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 SGD PMID 15477388
- ↑ Lee M, et al. (2000) Genetic analysis of the role of Pol II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast. Genetics 155(4):1535-42 SGD PMID 10924455
- ↑ Myers LC, et al. (1999) Mediator protein mutations that selectively abolish activated transcription. Proc Natl Acad Sci U S A 96(1):67-72 SGD PMID 9874773
- ↑ Papamichos-Chronakis M, et al. (2000) Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme. J Biol Chem 275(12):8397-403 SGD PMID 10722672
- ↑ Reeves WM and Hahn S (2003) Activator-independent functions of the yeast mediator sin4 complex in preinitiation complex formation and transcription reinitiation. Mol Cell Biol 23(1):349-58 SGD PMID 12482986
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