Difference between revisions of "YGL011C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGL011C YGL011C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002979 YGL011C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SCL1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SCL1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:475252..474494
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|nowrap| Chr VII:475247..474489
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002979
 
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'''Description of {{PAGENAME}}:''' Alpha subunit of the 20S core complex of the 26S proteasome involved in the degradation of ubiquitinated substrates; essential for growth; detected in the mitochondria<ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 {{SGDpaper|S000075100}} PMID 14576278</ref><ref name='S000056675'>Emori Y, et al. (1991) Molecular cloning and functional analysis of three subunits of yeast proteasome. Mol Cell Biol 11(1):344-53 {{SGDpaper|S000056675}} PMID 1898763</ref><ref name='S000044488'>Lee DH, et al. (1991) Molecular cloning of the yeast proteasome PRS2 gene identical to the suppressor gene scl1+. Biochem Int 23(4):689-96 {{SGDpaper|S000044488}} PMID 1872882</ref><ref name='S000040877'>Groll M, et al. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386(6624):463-71
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'''Description of YGL011C:''' Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria<ref name='S000056675'>Emori Y, et al. (1991) Molecular cloning and functional analysis of three subunits of yeast proteasome. Mol Cell Biol 11(1):344-53 {{SGDpaper|S000056675}} PMID 1898763</ref><ref name='S000040877'>Groll M, et al. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386(6624):463-71 {{SGDpaper|S000040877}} PMID 9087403</ref><ref name='S000044488'>Lee DH, et al. (1991) Molecular cloning of the yeast proteasome PRS2 gene identical to the suppressor gene scl1+. Biochem Int 23(4):689-96 {{SGDpaper|S000044488}} PMID 1872882</ref><ref name='S000075100'>Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
  {{SGDpaper|S000040877}} PMID 9087403</ref>
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  {{SGDpaper|S000075100}} PMID 14576278</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YGL011C
Gene name SCL1
Aliases PRC2
Feature type ORF, Verified
Coordinates Chr VII:475247..474489
Primary SGDID S000002979


Description of YGL011C: Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria[1][2][3][4]




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References

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  1. Emori Y, et al. (1991) Molecular cloning and functional analysis of three subunits of yeast proteasome. Mol Cell Biol 11(1):344-53 SGD PMID 1898763
  2. Groll M, et al. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386(6624):463-71 SGD PMID 9087403
  3. Lee DH, et al. (1991) Molecular cloning of the yeast proteasome PRS2 gene identical to the suppressor gene scl1+. Biochem Int 23(4):689-96 SGD PMID 1872882
  4. Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278

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