Difference between revisions of "YDR419W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002827 YDR419W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD30 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD30 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1303174..1305072 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002827 | ||
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| − | '''Description of | + | '''Description of YDR419W:''' DNA polymerase eta, involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV<ref name='S000046956'>Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 {{SGDpaper|S000046956}} PMID 9974380</ref><ref name='S000056153'>Masutani C, et al. (1999) The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature 399(6737):700-4 {{SGDpaper|S000056153}} PMID 10385124</ref><ref name='S000082204'>Prakash S, et al. (2005) Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem 74:317-53 {{SGDpaper|S000082204}} PMID 15952890</ref><ref name='S000051688'>Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000051688}} PMID 10713149</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR419W |
| Gene name | RAD30 |
| Aliases | DBH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1303174..1305072 |
| Primary SGDID | S000002827 |
Description of YDR419W: DNA polymerase eta, involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV[1][2][3][4]
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References
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- ↑ Johnson RE, et al. (1999) Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Science 283(5404):1001-4 SGD PMID 9974380
- ↑ Masutani C, et al. (1999) The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature 399(6737):700-4 SGD PMID 10385124
- ↑ Prakash S, et al. (2005) Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem 74:317-53 SGD PMID 15952890
- ↑ Yuan F, et al. (2000) Specificity of DNA lesion bypass by the yeast DNA polymerase eta. J Biol Chem 275(11):8233-9 SGD PMID 10713149
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