Difference between revisions of "YDR353W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002761 YDR353W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TRR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TRR1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1183299..1184258 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002761 |
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| − | '''Description of | + | '''Description of YDR353W:''' Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress<ref name='S000049388'>Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54 {{SGDpaper|S000049388}} PMID 9202020</ref><ref name='S000047291'>Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 {{SGDpaper|S000047291}} PMID 10037727</ref><ref name='S000059335'>Ross SJ, et al. (2000) Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol Biol Cell 11(8):2631-42 {{SGDpaper|S000059335}} PMID 10930459</ref><ref name='S000071764'>Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 {{SGDpaper|S000071764}} PMID 12410842</ref><ref name='S000073788'>Trotter EW and Grant CM (2003) Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems. EMBO Rep 4(2):184-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073788}} PMID 12612609</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR353W |
| Gene name | TRR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1183299..1184258 |
| Primary SGDID | S000002761 |
Description of YDR353W: Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress[1][2][3][4][5]
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Contents
Community Commentary
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References
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- ↑ Machado AK, et al. (1997) Thioredoxin reductase-dependent inhibition of MCB cell cycle box activity in Saccharomyces cerevisiae. J Biol Chem 272(27):17045-54 SGD PMID 9202020
- ↑ Pedrajas JR, et al. (1999) Identification and functional characterization of a novel mitochondrial thioredoxin system in Saccharomyces cerevisiae. J Biol Chem 274(10):6366-73 SGD PMID 10037727
- ↑ Ross SJ, et al. (2000) Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast. Mol Biol Cell 11(8):2631-42 SGD PMID 10930459
- ↑ Trotter EW and Grant CM (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78 SGD PMID 12410842
- ↑ Trotter EW and Grant CM (2003) Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems. EMBO Rep 4(2):184-8 SGD PMID 12612609
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