Difference between revisions of "YDR308C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR308C YDR308C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002716 YDR308C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SRB7 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SRB7 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1078445..1078023
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|nowrap| Chr IV:1078449..1078027
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002716
 
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'''Description of {{PAGENAME}}:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p<ref name='S000082023'>Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 {{SGDpaper|S000082023}} PMID 15896740</ref><ref name='S000053228'>Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 {{SGDpaper|S000053228}} PMID 11118219</ref><ref name='S000039384'>Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910
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'''Description of YDR308C:''' Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p<ref name='S000053228'>Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 {{SGDpaper|S000053228}} PMID 11118219</ref><ref name='S000039384'>Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 {{SGDpaper|S000039384}} PMID 7774808</ref><ref name='S000082023'>Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9
  {{SGDpaper|S000039384}} PMID 7774808</ref>
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  {{SGDpaper|S000082023}} PMID 15896740</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDR308C
Gene name SRB7
Aliases MED21
Feature type ORF, Verified
Coordinates Chr IV:1078449..1078027
Primary SGDID S000002716


Description of YDR308C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p[1][2][3]




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Community Commentary

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References

See Help:References on how to add references

  1. Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 SGD PMID 11118219
  2. Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 SGD PMID 7774808
  3. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740

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