Difference between revisions of "YDR263C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR263C YDR263C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002671 YDR263C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DIN7 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DIN7 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:995530..994238
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|nowrap| Chr IV:995534..994242
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002671
 
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'''Description of {{PAGENAME}}:''' Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination<ref name='S000073928'>Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 {{SGDpaper|S000073928}} PMID 12827502</ref><ref name='S000045102'>Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 {{SGDpaper|S000045102}} PMID 10628970</ref><ref name='S000043383'>Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 {{SGDpaper|S000043383}} PMID 9079876</ref><ref name='S000041233'>Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83
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'''Description of YDR263C:''' Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination<ref name='S000045102'>Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 {{SGDpaper|S000045102}} PMID 10628970</ref><ref name='S000073928'>Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 {{SGDpaper|S000073928}} PMID 12827502</ref><ref name='S000043383'>Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 {{SGDpaper|S000043383}} PMID 9079876</ref><ref name='S000041233'>Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83
 
  {{SGDpaper|S000041233}} PMID 9628902</ref>
 
  {{SGDpaper|S000041233}} PMID 9628902</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDR263C
Gene name DIN7
Aliases DIN3
Feature type ORF, Verified
Coordinates Chr IV:995534..994242
Primary SGDID S000002671


Description of YDR263C: Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination[1][2][3][4]




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References

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  1. Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 SGD PMID 10628970
  2. Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 SGD PMID 12827502
  3. Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 SGD PMID 9079876
  4. Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83 SGD PMID 9628902

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