Difference between revisions of "YDR062W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002469 YDR062W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''LCB2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''LCB2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:576474..578159 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002469 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002469 | ||
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| − | '''Description of YDR062W:''' Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine<ref name='S000055817'>Zhao C, et al. (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269(34):21480-8 {{SGDpaper|S000055817}} PMID 8063782 | + | '''Description of YDR062W:''' Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine<ref name='S000043517'>Nagiec MM, et al. (1994) The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis. Proc Natl Acad Sci U S A 91(17):7899-902 {{SGDpaper|S000043517}} PMID 8058731</ref><ref name='S000055817'>Zhao C, et al. (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269(34):21480-8 |
| − | + | {{SGDpaper|S000055817}} PMID 8063782</ref> | |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YDR062W |
| Gene name | LCB2 |
| Aliases | SCS1, TSC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:576474..578159 |
| Primary SGDID | S000002469 |
Description of YDR062W: Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine[1][2]
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References
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- ↑ Nagiec MM, et al. (1994) The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis. Proc Natl Acad Sci U S A 91(17):7899-902 SGD PMID 8058731
- ↑ Zhao C, et al. (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269(34):21480-8 SGD PMID 8063782
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