Difference between revisions of "YDR014W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR014W YDR014W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002421 YDR014W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD61 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RAD61 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''WPL1''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:474043..475986
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|nowrap| Chr IV:474046..475989
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002421
 
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'''Description of {{PAGENAME}}:''' Protein of unknown function; mutation confers radiation sensitivity<ref name='S000073736'>Game JC, et al. (2003) Use of a genome-wide approach to identify new genes that control resistance of Saccharomyces cerevisiae to ionizing radiation. Radiat Res 160(1):14-24
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'''Description of YDR014W:''' Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin<ref name='S000127217'>Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 {{SGDpaper|S000127217}} PMID 17113138</ref><ref name='S000127161'>Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 {{SGDpaper|S000127161}} PMID 18653893</ref><ref name='S000129839'>Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 {{SGDpaper|S000129839}} PMID 19328069</ref><ref name='S000129631'>Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7
  {{SGDpaper|S000073736}} PMID 12816519</ref>
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  {{SGDpaper|S000129631}} PMID 19268589</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDR014W
Gene name RAD61
Aliases WPL1
Feature type ORF, Verified
Coordinates Chr IV:474046..475989
Primary SGDID S000002421


Description of YDR014W: Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin[1][2][3][4]




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Community Commentary

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References

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  1. Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 SGD PMID 17113138
  2. Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 SGD PMID 18653893
  3. Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 SGD PMID 19328069
  4. Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 SGD PMID 19268589

See Help:Categories on how to add the wiki page for this gene to a Category </protect>