Difference between revisions of "YDL230W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDL230W YDL230W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002389 YDL230W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PTP1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PTP1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:42701..43708
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|nowrap| Chr IV:42700..43707
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002389
 
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'''Description of {{PAGENAME}}:''' Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria<ref name='S000048538'>Guan KL, et al. (1991) Cloning and expression of a yeast protein tyrosine phosphatase. J Biol Chem 266(20):12964-70 {{SGDpaper|S000048538}} PMID 1649172</ref><ref name='S000046580'>Wilson LK, et al. (1995) The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. J Biol Chem 270(42):25185-93
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'''Description of YDL230W:''' Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation<ref name='S000144907'>Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 {{SGDpaper|S000144907}} PMID 21460040</ref><ref name='S000048538'>Guan KL, et al. (1991) Cloning and expression of a yeast protein tyrosine phosphatase. J Biol Chem 266(20):12964-70 {{SGDpaper|S000048538}} PMID 1649172</ref><ref name='S000046580'>Wilson LK, et al. (1995) The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. J Biol Chem 270(42):25185-93
 
  {{SGDpaper|S000046580}} PMID 7559654</ref>
 
  {{SGDpaper|S000046580}} PMID 7559654</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDL230W
Gene name PTP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:42700..43707
Primary SGDID S000002389


Description of YDL230W: Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation[1][2][3]




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References

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  1. Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 SGD PMID 21460040
  2. Guan KL, et al. (1991) Cloning and expression of a yeast protein tyrosine phosphatase. J Biol Chem 266(20):12964-70 SGD PMID 1649172
  3. Wilson LK, et al. (1995) The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. J Biol Chem 270(42):25185-93 SGD PMID 7559654

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