Difference between revisions of "YDL216C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDL216C YDL216C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002375 YDL216C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RRI1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RRI1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:70320..68998
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|nowrap| Chr IV:70319..68997
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002375
 
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'''Description of {{PAGENAME}}:''' Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling<ref name='S000071980'>Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 {{SGDpaper|S000071980}} PMID 12446563</ref><ref name='S000071602'>Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 {{SGDpaper|S000071602}} PMID 12186635</ref><ref name='S000071600'>Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11
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'''Description of YDL216C:''' Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling<ref name='S000071600'>Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 {{SGDpaper|S000071600}} PMID 12183637</ref><ref name='S000071980'>Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 {{SGDpaper|S000071980}} PMID 12446563</ref><ref name='S000071602'>Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15
{{SGDpaper|S000071600}} PMID 12183637</ref>
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{{SGDpaper|S000071602}} PMID 12186635</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDL216C
Gene name RRI1
Aliases CSN5, JAB1
Feature type ORF, Verified
Coordinates Chr IV:70319..68997
Primary SGDID S000002375


Description of YDL216C: Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling[1][2][3]




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References

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  1. Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 SGD PMID 12183637
  2. Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
  3. Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 SGD PMID 12186635

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