Difference between revisions of "YDL128W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002286 YDL128W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VCX1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VCX1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:232652..233887 | |nowrap| Chr IV:232652..233887 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002286 | ||
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| − | '''Description of | + | '''Description of YDL128W:''' Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity, involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter<ref name='S000135694'>Cagnac O, et al. (2010) Vacuolar cation/H+ antiporters of Saccharomyces cerevisiae. J Biol Chem 285(44):33914-22 {{SGDpaper|S000135694}} PMID 20709757</ref><ref name='S000046399'>Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 {{SGDpaper|S000046399}} PMID 8628289</ref><ref name='S000046126'>Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6 {{SGDpaper|S000046126}} PMID 10371152</ref><ref name='S000041805'>Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41 |
{{SGDpaper|S000041805}} PMID 8668190</ref> | {{SGDpaper|S000041805}} PMID 8668190</ref> | ||
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDL128W |
| Gene name | VCX1 |
| Aliases | HUM1, MNR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:232652..233887 |
| Primary SGDID | S000002286 |
Description of YDL128W: Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity, involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter[1][2][3][4]
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Community Commentary
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References
See Help:References on how to add references
- ↑ Cagnac O, et al. (2010) Vacuolar cation/H+ antiporters of Saccharomyces cerevisiae. J Biol Chem 285(44):33914-22 SGD PMID 20709757
- ↑ Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 SGD PMID 8628289
- ↑ Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6 SGD PMID 10371152
- ↑ Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41 SGD PMID 8668190
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