Difference between revisions of "YDL101C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002259 YDL101C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DUN1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DUN1 '' | ||
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| − | '''Description of YDL101C:''' Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair<ref name='S000060279'>Blanchard H, et al. (2001) Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases. Acta Crystallogr D Biol Crystallogr 57(Pt 3):459-61 {{SGDpaper|S000060279}} PMID 11223532 | + | '''Description of YDL101C:''' Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair<ref name='S000072668'>Bashkirov VI, et al. (2003) Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol 23(4):1441-52 {{SGDpaper|S000072668}} PMID 12556502</ref><ref name='S000060279'>Blanchard H, et al. (2001) Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases. Acta Crystallogr D Biol Crystallogr 57(Pt 3):459-61 {{SGDpaper|S000060279}} PMID 11223532</ref><ref name='S000070046'>Hammet A, et al. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J Biol Chem 277(25):22469-74 {{SGDpaper|S000070046}} PMID 11953437</ref><ref name='S000069725'>Zhao X and Rothstein R (2002) The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A 99(6):3746-51 |
| − | {{SGDpaper| | + | {{SGDpaper|S000069725}} PMID 11904430</ref> |
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Latest revision as of 06:45, 23 January 2012
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| Systematic name | YDL101C |
| Gene name | DUN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:281848..280307 |
| Primary SGDID | S000002259 |
Description of YDL101C: Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair[1][2][3][4]
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References
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- ↑ Bashkirov VI, et al. (2003) Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol 23(4):1441-52 SGD PMID 12556502
- ↑ Blanchard H, et al. (2001) Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases. Acta Crystallogr D Biol Crystallogr 57(Pt 3):459-61 SGD PMID 11223532
- ↑ Hammet A, et al. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J Biol Chem 277(25):22469-74 SGD PMID 11953437
- ↑ Zhao X and Rothstein R (2002) The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A 99(6):3746-51 SGD PMID 11904430
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