Difference between revisions of "YDL060W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDL060W YDL060W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002218 YDL060W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TSR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TSR1 ''
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|nowrap| Chr IV:341619..343985
 
|nowrap| Chr IV:341619..343985
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002218
 
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'''Description of {{PAGENAME}}:''' Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles<ref name='S000076341'>Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 {{SGDpaper|S000076341}} PMID 15167894</ref><ref name='S000065947'>Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83
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'''Description of YDL060W:''' Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p<ref name='S000065947'>Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83 {{SGDpaper|S000065947}} PMID 11565749</ref><ref name='S000076341'>Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 {{SGDpaper|S000076341}} PMID 15167894</ref><ref name='S000146441'>Strunk BS, et al. (2011) Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science ()
  {{SGDpaper|S000065947}} PMID 11565749</ref>
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  {{SGDpaper|S000146441}} PMID 21835981</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 06:45, 23 January 2012

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Systematic name YDL060W
Gene name TSR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:341619..343985
Primary SGDID S000002218


Description of YDL060W: Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p[1][2][3]




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References

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  1. Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83 SGD PMID 11565749
  2. Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 SGD PMID 15167894
  3. Strunk BS, et al. (2011) Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science () SGD PMID 21835981

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