Difference between revisions of "YDL060W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002218 YDL060W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TSR1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TSR1 '' | ||
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| − | '''Description of YDL060W:''' Protein required for processing of 20S pre-rRNA in the cytoplasm | + | '''Description of YDL060W:''' Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p<ref name='S000065947'>Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83 {{SGDpaper|S000065947}} PMID 11565749</ref><ref name='S000076341'>Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 {{SGDpaper|S000076341}} PMID 15167894</ref><ref name='S000146441'>Strunk BS, et al. (2011) Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146441}} PMID 21835981</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDL060W |
| Gene name | TSR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:341619..343985 |
| Primary SGDID | S000002218 |
Description of YDL060W: Protein required for processing of 20S pre-rRNA in the cytoplasm; associates with pre-40S ribosomal particles; inhibits the premature association of 60S subunits with assembling 40S subunits in the cytoplasm; similar to Bms1p[1][2][3]
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References
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- ↑ Gelperin D, et al. (2001) Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast. RNA 7(9):1268-83 SGD PMID 11565749
- ↑ Leger-Silvestre I, et al. (2004) The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J 23(12):2336-47 SGD PMID 15167894
- ↑ Strunk BS, et al. (2011) Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science () SGD PMID 21835981
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