Difference between revisions of "YDL044C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (10 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN--> | ||
{{PageTop}} | {{PageTop}} | ||
| + | <protect> | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002202 YDL044C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTF2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MTF2 '' | ||
| Line 12: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:375289..373967 |
|- | |- | ||
| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002202 |
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YDL044C:''' Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription<ref name='S000050801'>Asher EB, et al. (1989) Novel class of nuclear genes involved in both mRNA splicing and protein synthesis in Saccharomyces cerevisiae mitochondria. Mol Gen Genet 215(3):517-28 {{SGDpaper|S000050801}} PMID 2651895</ref><ref name='S000060339'>Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 {{SGDpaper|S000060339}} PMID 11118450</ref><ref name='S000039394'>Wallis MG, et al. (1994) The NAM1 protein (NAM1p), which is selectively required for cox1, cytb and atp6 transcript processing/stabilisation, is located in the yeast mitochondrial matrix. Eur J Biochem 222(1):27-32 |
{{SGDpaper|S000039394}} PMID 8200349</ref> | {{SGDpaper|S000039394}} PMID 8200349</ref> | ||
<br> | <br> | ||
| Line 23: | Line 24: | ||
<br> | <br> | ||
<br> | <br> | ||
| − | + | <br> | |
| + | </protect> | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Genetic ==== | ||
| + | [[Category:Topic:Interactions:Genetic]] | ||
| + | YDL044C is suppressed by SLS1 [[Category:Genetic Interaction with SLS1]] | ||
| + | |||
| + | |||
| + | '''Strain Background''': DBY2006<br> | ||
| + | '''Genotype''': ACB1<br> | ||
| + | '''Mutation type(s)''': null | ||
| + | |||
| + | The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. <ref name='S000069068'>Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 {{SGDpaper|S000069068}} PMID 11805046</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with RPO41 [[Category:Two Hybrid Interactions with RPO41]]<br> | ||
| + | The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. <ref name='S000060339'>Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 {{SGDpaper|S000060339}} PMID 11118450</ref> <ref name = 'CAset5293-2003-06-05'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=5293 Gerald Shadel] on 2003-06-05</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | |||
| + | |||
| + | |||
| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| + | <!-- | ||
| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
| + | --> | ||
| + | |||
| + | |||
| + | <protect> | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
| + | </protect> | ||
Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDL044C |
| Gene name | MTF2 |
| Aliases | NAM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:375289..373967 |
| Primary SGDID | S000002202 |
Description of YDL044C: Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription[1][2][3]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
YDL044C is suppressed by SLS1
Strain Background: DBY2006
Genotype: ACB1
Mutation type(s): null
The mitochondrial membrane protein Sls1p suppresses the petite phenotype of mtRNA polymerase (Rpo41p) amino-terminal domain and a mtf2/nam1 null mutations, indicating that transcription and tranlation of mtDNA-encoded genes occurs coordinately at the inner mitochondrial membrane. [4] [5]
Two Hybrid
Two Hybrid interaction with RPO41
The mitochondrial matrix protein Mtf2p/Nam1p interacts with the amino-terminal domain of mtRNA polymerase (Rpo41p) to couple post-transcriptional events to transcription during mitochondrial gene expression. [2] [5]
<protect>
References
See Help:References on how to add references
- ↑ Asher EB, et al. (1989) Novel class of nuclear genes involved in both mRNA splicing and protein synthesis in Saccharomyces cerevisiae mitochondria. Mol Gen Genet 215(3):517-28 SGD PMID 2651895
- ↑ 2.0 2.1 Rodeheffer MS, et al. (2001) Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J Biol Chem 276(11):8616-22 SGD PMID 11118450
- ↑ Wallis MG, et al. (1994) The NAM1 protein (NAM1p), which is selectively required for cox1, cytb and atp6 transcript processing/stabilisation, is located in the yeast mitochondrial matrix. Eur J Biochem 222(1):27-32 SGD PMID 8200349
- ↑ Bryan AC, et al. (2002) Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160(1):75-82 SGD PMID 11805046
- ↑ 5.0 5.1 submitted by Gerald Shadel on 2003-06-05
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
