Difference between revisions of "YFR052W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001948 YFR052W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RPN12 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RPN12 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr VI: | + | |nowrap| Chr VI:252505..253329 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001948 | ||
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| − | '''Description of | + | '''Description of YFR052W:''' Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p<ref name='S000039347'>Takeuchi J and Toh-e A (1999) Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic lethality. Mol Gen Genet 262(1):145-53 {{SGDpaper|S000039347}} PMID 10503546</ref><ref name='S000054953'>Tone Y, et al. (2000) Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells. Gene 243(1-2):37-45 |
| − | {{SGDpaper| | + | {{SGDpaper|S000054953}} PMID 10675611</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 06:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFR052W |
| Gene name | RPN12 |
| Aliases | NIN1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:252505..253329 |
| Primary SGDID | S000001948 |
Description of YFR052W: Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p[1][2]
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References
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- ↑ Takeuchi J and Toh-e A (1999) Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic lethality. Mol Gen Genet 262(1):145-53 SGD PMID 10503546
- ↑ Tone Y, et al. (2000) Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells. Gene 243(1-2):37-45 SGD PMID 10675611
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