Difference between revisions of "YFR052W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001948 YFR052W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001948 YFR052W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN12 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN12 ''

Latest revision as of 06:45, 23 January 2012

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Systematic name YFR052W
Gene name RPN12
Aliases NIN1
Feature type ORF, Verified
Coordinates Chr VI:252505..253329
Primary SGDID S000001948


Description of YFR052W: Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p[1][2]




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References

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  1. Takeuchi J and Toh-e A (1999) Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic lethality. Mol Gen Genet 262(1):145-53 SGD PMID 10503546
  2. Tone Y, et al. (2000) Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells. Gene 243(1-2):37-45 SGD PMID 10675611

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