Difference between revisions of "YFR044C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001940 YFR044C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DUG1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DUG1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr VI: | + | |nowrap| Chr VI:241437..239992 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001940 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001940 | ||
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− | '''Description of YFR044C:''' | + | '''Description of YFR044C:''' Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)<ref name='S000120080'>Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 {{SGDpaper|S000120080}} PMID 17179087</ref><ref name='S000129858'>Kaur H, et al. (2009) Dug1p Is a Cys-Gly Peptidase of the {gamma}-Glutamyl Cycle of Saccharomyces cerevisiae and Represents a Novel Family of Cys-Gly Peptidases. J Biol Chem 284(21):14493-502 |
− | {{SGDpaper| | + | {{SGDpaper|S000129858}} PMID 19346245</ref> |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
Systematic name | YFR044C |
Gene name | DUG1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VI:241437..239992 |
Primary SGDID | S000001940 |
Description of YFR044C: Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)[1][2]
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Community Commentary
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [3] [4]
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References
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- ↑ Ganguli D, et al. (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 SGD PMID 17179087
- ↑ Kaur H, et al. (2009) Dug1p Is a Cys-Gly Peptidase of the {gamma}-Glutamyl Cycle of Saccharomyces cerevisiae and Represents a Novel Family of Cys-Gly Peptidases. J Biol Chem 284(21):14493-502 SGD PMID 19346245
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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