Difference between revisions of "YFL010C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YFL010C YFL010C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001884 YFL010C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''WWM1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''WWM1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VI:115737..115102
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|nowrap| Chr VI:115743..115108
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001884
 
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'''Description of {{PAGENAME}}:''' WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1<ref name='S000082266'>Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 {{SGDpaper|S000082266}} PMID 11274415</ref><ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 {{SGDpaper|S000070033}} PMID 11983181</ref><ref name='S000069959'>Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 {{SGDpaper|S000069959}} PMID 12062425</ref><ref name='S000043128'>Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7
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'''Description of YFL010C:''' WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1<ref name='S000070033'>Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 {{SGDpaper|S000070033}} PMID 11983181</ref><ref name='S000082266'>Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 {{SGDpaper|S000082266}} PMID 11274415</ref><ref name='S000069959'>Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 {{SGDpaper|S000069959}} PMID 12062425</ref><ref name='S000043128'>Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7
 
  {{SGDpaper|S000043128}} PMID 10688190</ref>
 
  {{SGDpaper|S000043128}} PMID 10688190</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YFL010C
Gene name WWM1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:115743..115108
Primary SGDID S000001884


Description of YFL010C: WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1[1][2][3][4]




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References

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  1. Madeo F, et al. (2002) A caspase-related protease regulates apoptosis in yeast. Mol Cell 9(4):911-7 SGD PMID 11983181
  2. Stevenson LF, et al. (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51 SGD PMID 11274415
  3. Szallies A, et al. (2002) A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. FEBS Lett 517(1-3):144-50 SGD PMID 12062425
  4. Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 SGD PMID 10688190

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