Difference between revisions of "YKR019C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001727 YKR019C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IRS4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''IRS4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
− | |nowrap| Chr XI: | + | |nowrap| Chr XI:478063..476216 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001727 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001727 | ||
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− | '''Description of YKR019C:''' | + | '''Description of YKR019C:''' EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS<ref name='S000125665'>Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69 {{SGDpaper|S000125665}} PMID 18298591</ref><ref name='S000040062'>Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 {{SGDpaper|S000040062}} PMID 9822599</ref><ref name='S000054483'>Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 |
{{SGDpaper|S000054483}} PMID 10082585</ref> | {{SGDpaper|S000054483}} PMID 10082585</ref> | ||
<br> | <br> |
Latest revision as of 07:45, 23 January 2012
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Systematic name | YKR019C |
Gene name | IRS4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XI:478063..476216 |
Primary SGDID | S000001727 |
Description of YKR019C: EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS[1][2][3]
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References
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- ↑ Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69 SGD PMID 18298591
- ↑ Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 SGD PMID 9822599
- ↑ Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 SGD PMID 10082585
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