Difference between revisions of "YKL084W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001567 YKL084W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HOT13 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HOT13 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XI: | + | |nowrap| Chr XI:280509..280859 |
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001567 |
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| − | '''Description of | + | '''Description of YKL084W:''' Zinc-binding mitochondrial intermembrane space (IMS) protein involved in a disulfide relay system for IMS import of cysteine-containing proteins; binds Mia40p and stimulates its Erv1p-dependent oxidation, probably by sequestering zinc<ref name='S000077347'>Curran SP, et al. (2004) The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway. J Biol Chem 279(42):43744-51 {{SGDpaper|S000077347}} PMID 15294910</ref><ref name='S000135685'>Mesecke N, et al. (2008) The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40. EMBO Rep 9(11):1107-13 |
| − | {{SGDpaper| | + | {{SGDpaper|S000135685}} PMID 18787558</ref> |
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==Community Commentary== | ==Community Commentary== | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKL084W |
| Gene name | HOT13 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:280509..280859 |
| Primary SGDID | S000001567 |
Description of YKL084W: Zinc-binding mitochondrial intermembrane space (IMS) protein involved in a disulfide relay system for IMS import of cysteine-containing proteins; binds Mia40p and stimulates its Erv1p-dependent oxidation, probably by sequestering zinc[1][2]
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Contents
Community Commentary
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References
See Help:References on how to add references
- ↑ Curran SP, et al. (2004) The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway. J Biol Chem 279(42):43744-51 SGD PMID 15294910
- ↑ Mesecke N, et al. (2008) The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40. EMBO Rep 9(11):1107-13 SGD PMID 18787558
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